Publications

Find out what we've been working on and check out our publications!

2024

2024

Poor olfaction prior to cardiac surgery: Association with cognition, plasma neurofilament light, and post-operative delirium.

Kamath V, Yanek LR, Neufeld KJ, Lewis A, Aziz H, Le LM, Tian J, Moghekar A, Hogue CW Jr, Brown CH 4th.

Int J Geriatr Psychiatry. 2024 Feb;39(2):e6066. doi: 10.1002/gps.6066.

PMID: 38314872

Association of Plasma Markers of Alzheimer's Disease, Neurodegeneration, and Neuroinflammation with the Choroid Plexus Integrity in Aging.

Bouhrara M, Walker KA, R Alisch JS, Gong Z, Mazucanti CH, Lewis A, Moghekar AR, Turek L, Collingham V, Shehadeh N, Fantoni G, Kaileh M, Bergeron CM, Bergeron J, Resnick SM, Egan JM.

Aging Dis. 2024 Jan 8. doi: 10.14336/AD.2023.1226. Online ahead of print.

PMID: 38300640

2023

Plasma p-tau212: antemortem diagnostic performance and prediction of autopsy verification of Alzheimer's disease neuropathology.

Kac PR, González-Ortiz F, Emeršič A, Dulewicz M, Koutarapu S, Turton M, An Y, Smirnov D, Kulczyńska-Przybik A, Varma V, Ashton NJ, Montoliu-Gaya L, Camporesi E, Winkel I, Paradowski B, Moghekar A, Troncoso JC, Brinkmalm G, Resnick SM, Mroczko B, Kvartsberg H, Kramberger MG, Hanrieder J, Čučnik S, Harrison P, Zetterberg H, Lewczuk P, Thambisetty M, Rot U, Galasko D, Blennow K, Karikari TK.

medRxiv. 2023 Dec 11:2023.12.11.23299806. doi: 10.1101/2023.12.11.23299806. Preprint.

PMID: 38168323 Free PMC article.

Proteomic Indicators of Health Predict Alzheimer's Disease Biomarker Levels and Dementia Risk.

Dark HE, Paterson C, Daya GN, Peng Z, Duggan MR, Bilgel M, An Y, Moghekar A, Davatzikos C, Resnick SM, Loupy K, Simpson M, Candia J, Mosley T, Coresh J, Palta P, Ferrucci L, Shapiro A, Williams SA, Walker KA.

Ann Neurol. 2023 Oct 6. doi: 10.1002/ana.26817. Online ahead of print.

PMID: 37801487

Identification of Clinically Relevant Brain Endothelial Cell Biomarkers in Plasma.

Cordon J, Duggan MR, Gomez GT, Pucha KA, Peng Z, Dark HE, Davatzikos C, Erus G, Lewis A, Moghekar A, Candia J, Ferrucci L, Kapogiannis D, Walker KA.

Stroke. 2023 Nov;54(11):2853-2863. doi: 10.1161/STROKEAHA.123.043908. Epub 2023 Oct 10.

PMID: 37814955

Placental growth factor as a sensitive biomarker for vascular cognitive impairment.

Hinman JD, Elahi F, Chong D, Radabaugh H, Ferguson A, Maillard P, Thompson JF, Rosenberg GA, Sagare A, Moghekar A, Lu H, Lee T, Wilcock D, Satizabal CL, Tracy R, Seshadri S, Schwab K, Helmer K, Singh H, Kivisäkk P, Greenberg S, DeCarli C, Kramer J.

Alzheimers Dement. 2023 Aug;19(8):3519-3527. doi: 10.1002/alz.12974. Epub 2023 Feb 23.

PMID: 36815663

NPTX2 in Cerebrospinal Fluid Predicts the Progression From Normal Cognition to Mild Cognitive Impairment.

Soldan A, Oh S, Ryu T, Pettigrew C, Zhu Y, Moghekar A, Xiao MF, Pontone GM, Albert M, Na CH, Worley P.

Ann Neurol. 2023 Oct;94(4):620-631. doi: 10.1002/ana.26725. Epub 2023 Jul 25.

PMID: 37345460

Skeletal muscle mitochondrial function predicts cognitive impairment and is associated with biomarkers of Alzheimer's disease and neurodegeneration.

Tian Q, Bilgel M, Walker KA, Moghekar AR, Fishbein KW, Spencer RG, Resnick SM, Ferrucci L.

Alzheimers Dement. 2023 Oct;19(10):4436-4445. doi: 10.1002/alz.13388. Epub 2023 Aug 2.

PMID: 37530130

Association of perioperative plasma concentration of neurofilament light with delirium after cardiac surgery: a nested observational study.

Brown CH, Kim AS, Yanek L, Lewis A, Mandal K, Le L, Tian J, Neufeld KJ, Hogue C, Moghekar A.

Br J Anaesth. 2023 Dec 18:S0007-0912(23)00638-4. doi: 10.1016/j.bja.2023.10.043. Online ahead of print.

PMID: 38114355

Application and validation of an algorithmic classification of early impairment in cognitive performance.

Cai Y, Schrack JA, Agrawal Y, Armstrong NM, Wanigatunga A, Kitner-Triolo M, Moghekar A, Ferrucci L, Simonsick EM, Resnick SM, Gross AL.

Aging Ment Health. 2023 Nov-Dec;27(11):2187-2192. doi: 10.1080/13607863.2023.2227118. Epub 2023 Jun 24.

PMID: 37354067

Loss of TDP-43 splicing repression occurs early in the aging population and is associated with Alzheimer's disease neuropathologic changes and cognitive decline.

Chang K, Ling JP, Redding-Ochoa J, An Y, Li L, Dean SA, Blanchard TG, Pylyukh T, Barrett A, Irwin KE, Moghekar A, Resnick SM, Wong PC, Troncoso JC.

Acta Neuropathol. 2023 Dec 22;147(1):4. doi: 10.1007/s00401-023-02653-2.

PMID: 38133681

The association between personality and plasma biomarkers of astrogliosis and neuronal injury.

Terracciano A, Walker K, An Y, Luchetti M, Stephan Y, Moghekar AR, Sutin AR, Ferrucci L, Resnick SM.

Neurobiol Aging. 2023 Aug;128:65-73. doi: 10.1016/j.neurobiolaging.2023.04.011. Epub 2023 Apr 25.

PMID: 37210782

Correction to: Plasma proteins related to inflammatory diet predict future cognitive impairment.

Duggan MR, Butler L, Peng Z, Daya GN, Moghekar A, An Y, Rapp SR, Hayden KM, Shadyab AH, Natale G, Liu L, Snetselaar L, Moaddel R, Rebholz CM, Sullivan K, Ballantyne CM, Resnick SM, Ferrucci L, Walker KA.

Mol Psychiatry. 2023 Apr;28(4):1610. doi: 10.1038/s41380-023-02007-0.

PMID: 36849825 Free PMC article. No abstract available.

Placental growth factor as a sensitive biomarker for vascular cognitive impairment.

Alzheimers Dement. 2023 Feb 23. doi: 10.1002/alz.12974. Online ahead of print.

PMID: 36815663

A fluid biomarker reveals loss of TDP-43 splicing repression in pre-symptomatic ALS.

Irwin KE, Jasin P, Braunstein KE, Sinha I, Bowden KD, Moghekar A, Oh ES, Raitcheva D, Bartlett D, Berry JD, Traynor B, Ling JP, Wong PC.

bioRxiv. 2023 Jan 24:2023.01.23.525202. doi: 10.1101/2023.01.23.525202. Preprint.

PMID: 36789434 Free PMC article.

MRI and fluid biomarkers reveal determinants of myelin and axonal loss with aging.

Walker KA, Duggan MR, Gong Z, Dark HE, Laporte JP, Faulkner ME, An Y, Lewis A, Moghekar AR, Resnick SM, Bouhrara M.

Ann Clin Transl Neurol. 2023 Mar;10(3):397-407. doi: 10.1002/acn3.51730. Epub 2023 Feb 10.

PMID: 36762407 Free PMC article.

Four-dimensional proteomics analysis of human cerebrospinal fluid with trapped ion mobility spectrometry using PASEF.

Mun DG, Budhraja R, Bhat FA, Zenka RM, Johnson KL, Moghekar A, Pandey A.

Proteomics. 2023 May;23(10):e2200507. doi: 10.1002/pmic.202200507. Epub 2023 Feb 19.

PMID: 36752121

Regional White Matter Hyperintensities and Alzheimer's Disease Biomarkers Among Older Adults with Normal Cognition and Mild Cognitive Impairment.

Newton P, Tchounguen J, Pettigrew C, Lim C, Lin Z, Lu H, Moghekar A, Albert M, Soldan A; BIOCARD Research Team.

J Alzheimers Dis. 2023;92(1):323-339. doi: 10.3233/JAD-220846.

PMID: 36744337 Free PMC article.

Plasma proteins related to inflammatory diet predict future cognitive impairment.

Mol Psychiatry. 2023 Apr;28(4):1599-1609. doi: 10.1038/s41380-023-01975-7. Epub 2023 Feb 3.

PMID: 36737481 Free PMC article.

Neurofilament Light and Cognition after Cardiac Surgery: Reply.

Brown CH, Hogue CW, Moghekar A.

Anesthesiology. 2023 Jun 1;138(6):663-664. doi: 10.1097/ALN.0000000000004484.

PMID: 36734810 No abstract available.

Longitudinal changes in Alzheimer's-related plasma biomarkers and brain amyloid.

Bilgel M, An Y, Walker KA, Moghekar AR, Ashton NJ, Kac PR, Karikari TK, Blennow K, Zetterberg H, Jedynak BM, Thambisetty M, Ferrucci L, Resnick SM.

medRxiv. 2023 Apr 21:2023.01.12.23284439. doi: 10.1101/2023.01.12.23284439. Preprint.

PMID: 36711545 Free PMC article. Updated.

Placebo-Controlled Effectiveness of Idiopathic Normal Pressure Hydrocephalus Shunting: A Randomized Pilot Trial.

Luciano M, Holubkov R, Williams MA, Malm J, Nagel S, Moghekar A, Eklund A, Zwimpfer T, Katzen H, Hanley DF, Hamilton MG; PENS Co-investigators and AHCRN Site PIs.

Neurosurgery. 2023 Mar 1;92(3):481-489. doi: 10.1227/neu.0000000000002225. Epub 2022 Nov 25.

PMID: 36700738 Clinical Trial.

Inpatient healthcare burden and variables influencing hydrocephalus-related admissions across the lifespan.

Koschnitzky JE, Yap E, Zhang Y, Chau MJ, Yerneni K, Somera AL, Luciano M, Moghekar A.

J Neurosurg. 2022 Dec 9:1-10. doi: 10.3171/2022.10.JNS22330. Online ahead of print.

PMID: 36681977

Cognitive impairment in chronic migraine compared to pseudotumor cerebri.

Fermo OP, Zhang Y, Wang J, Moghekar AR.

Neurol Neurochir Pol. 2023;57(2):189-197. doi: 10.5603/PJNNS.a2023.0002. Epub 2023 Jan 18.

PMID: 36651470

Health Conditions Associated with Alzheimer's Disease and Vascular Dementia.

Beason-Held LL, Kerley CI, Chaganti S, Moghekar A, Thambisetty M, Ferrucci L, Resnick SM, Landman BA.

Ann Neurol. 2023 Apr;93(4):805-818. doi: 10.1002/ana.26584. Epub 2023 Jan 18.

PMID: 36571386

2022

MRI assessment of cerebral oxygen extraction fraction in the medial temporal lobe.

Jiang D, Liu P, Lin Z, Hazel K, Pottanat G, Lucke E, Moghekar A, Pillai JJ, Lu H.

Neuroimage. 2023 Feb 1;266:119829. doi: 10.1016/j.neuroimage.2022.119829. Epub 2022 Dec 21.

PMID: 36565971 Free PMC article.

18.

Longitudinal CSF Alzheimer's disease biomarker changes from middle age to late adulthood.

Pettigrew C, Soldan A, Wang J, Wang MC, Greenberg B, Albert M, Moghekar A; BIOCARD Research Team.

Alzheimers Dement (Amst). 2022 Nov 18;14(1):e12374. doi: 10.1002/dad2.12374. eCollection 2022.

PMID: 36415591 Free PMC article.

19.

Ubiquitin-positive astrogliopathy clinically mimicking Parkinson's disease.

Morris M, Moghekar A, Guo H, Pletnikova O, Redding-Ochoa J, Albert M, Resnick SM, Chen L.

Acta Neuropathol Commun. 2022 Nov 14;10(1):164. doi: 10.1186/s40478-022-01464-y.

PMID: 36376970 Free PMC article.

CSF Alzheimer Disease Biomarkers: Time-Varying Relationships With MCI Symptom Onset and Associations With Age, Sex, and ApoE4.

Greenberg BD, Pettigrew C, Soldan A, Wang J, Wang MC, Darrow JA, Albert MS, Moghekar A.

Neurology. 2022 Oct 11;99(15):e1640-e1650. doi: 10.1212/WNL.0000000000200953.

PMID: 36216518

Herpes Viruses in the Baltimore Longitudinal Study of Aging: Associations With Brain Volumes, Cognitive Performance, and Plasma Biomarkers.

Duggan MR, Peng Z, An Y, Kitner Triolo MH, Shafer AT, Davatzikos C, Erus G, Karikkineth A, Lewis A, Moghekar A, Walker KA.

Neurology. 2022 Aug 19:10.1212/WNL.0000000000201036. doi: 10.1212/WNL.0000000000201036. Online ahead of print.

PMID: 35985823

Perioperative Neurofilament Light Plasma Concentrations and Cognition before and after Cardiac Surgery: A Prospective Nested Cohort Study.

Brown CH, Lewis A, Probert J, Parish M, Tian J, Mandal K, Everett A, Colantuoni E, Kamath V, Hogue C, Moghekar A.

Anesthesiology. 2022 Sep 1;137(3):303-314. doi: 10.1097/ALN.0000000000004327.

PMID: 35984933

Causal links among amyloid, tau, and neurodegeneration.

Bilgel M, Wong DF, Moghekar AR, Ferrucci L, Resnick SM; Alzheimer’s Disease Neuroimaging Initiative.

Brain Commun. 2022 Jul 25;4(4):fcac193. doi: 10.1093/braincomms/fcac193. eCollection 2022.

PMID: 35938073

Identification of the NRF2 transcriptional network as a therapeutic target for trigeminal neuropathic pain.

Vasavda C, Xu R, Liew J, Kothari R, Dhindsa RS, Semenza ER, Paul BD, Green DP, Sabbagh MF, Shin JY, Yang W, Snowman AM, Albacarys LK, Moghekar A, Pardo-Villamizar CA, Luciano M, Huang J, Bettegowda C, Kwatra SG, Dong X, Lim M, Snyder SH.

Sci Adv. 2022 Aug 5;8(31):eabo5633. doi: 10.1126/sciadv.abo5633. Epub 2022 Aug 3.

PMID: 35921423 Free PMC article.

Structural and Functional Brain Connectivity Uniquely Contribute to Episodic Memory Performance in Older Adults.

Alm KH, Soldan A, Pettigrew C, Faria AV, Hou X, Lu H, Moghekar A, Mori S, Albert M, Bakker A.

Front Aging Neurosci. 2022 Jul 12;14:951076. doi: 10.3389/fnagi.2022.951076. eCollection 2022.

PMID: 35903538 Free PMC article.

Multi-method investigation of factors influencing amyloid onset and impairment in three cohorts.

Betthauser TJ, Bilgel M, Koscik RL, Jedynak BM, An Y, Kellett KA, Moghekar A, Jonaitis EM, Stone CK, Engelman CD, Asthana S, Christian BT, Wong DF, Albert M, Resnick SM, Johnson SC; Alzheimer’s Disease Neuroimaging Initiative.

Brain. 2022 Jul 20:awac213. doi: 10.1093/brain/awac213. Online ahead of print.

PMID: 35856240

Longitudinal changes in brain oxygen extraction fraction (OEF) in older adults: Relationship to markers of vascular and Alzheimer's pathology.

Lin Z, Lim C, Jiang D, Soldan A, Pettigrew C, Oishi K, Zhu Y, Moghekar A, Liu P, Albert M, Lu H.

Alzheimers Dement. 2022 Jul 6. doi: 10.1002/alz.12727. Online ahead of print.

PMID: 35791732

Blood-brain barrier permeability in response to caffeine challenge.

Lin Z, Jiang D, Liu P, Ge Y, Moghekar A, Lu H.

Magn Reson Med. 2022 Nov;88(5):2259-2266. doi: 10.1002/mrm.29355. Epub 2022 Jun 26.

PMID: 35754146

CSF Biomarkers Predict Gait Outcomes in Idiopathic Normal Pressure Hydrocephalus.

Darrow JA, Lewis A, Gulyani S, Khingelova K, Rao A, Wang J, Zhang Y, Luciano M, Yasar S, Moghekar A.

Neurol Clin Pract. 2022 Apr;12(2):91-101. doi: 10.1212/CPJ.0000000000001156.

PMID: 35733946 Free PMC article.

The Clinical Utility of the MOCA in iNPH Assessment.

Wesner E, Etzkorn L, Bakre S, Chen J, Davis A, Zhang Y, Yasar S, Rao A, Luciano M, Wang J, Moghekar A.

Front Neurol. 2022 May 23;13:887669. doi: 10.3389/fneur.2022.887669. eCollection 2022.

PMID: 35677341 Free PMC article.

Daily Physical Activity Patterns as a Window on Cognitive Diagnosis in the Baltimore Longitudinal Study of Aging (BLSA).

Wanigatunga AA, Liu F, Wang H, Urbanek JK, An Y, Spira AP, Dougherty RJ, Tian Q, Moghekar A, Ferrucci L, Simonsick EM, Resnick SM, Schrack JA.

J Alzheimers Dis. 2022;88(2):459-469. doi: 10.3233/JAD-215544.

PMID: 35599480

AutoInFocus, a new paradigm for ultrasound-guided spine intervention: a multi-platform validation study.

Xu K, Jiang B, Moghekar A, Kazanzides P, Boctor E.

Int J Comput Assist Radiol Surg. 2022 May;17(5):911-920. doi: 10.1007/s11548-022-02583-6. Epub 2022 Mar 25.

PMID: 35334043

Safety and effectiveness of the assessment and treatment of idiopathic normal pressure hydrocephalus in the Adult Hydrocephalus Clinical Research Network.

Williams MA, Nagel SJ, Golomb J, Jensen H, Dasher NA, Holubkov R, Edwards RJ, Luciano MG, Zwimpfer TJ, Katzen H, Moghekar A, Wisoff JH, McKhann GM, Hamilton MG.

J Neurosurg. 2022 Mar 11:1-13. doi: 10.3171/2022.1.JNS212782. Online ahead of print.

PMID: 35276651

Olfaction, Cognitive Impairment, and PET Biomarkers in Community-Dwelling Older Adults.

Tian Q, Bilgel M, Moghekar AR, Ferrucci L, Resnick SM.

J Alzheimers Dis. 2022;86(3):1275-1285. doi: 10.3233/JAD-210636.

PMID: 35180111

Reassessing accuracy of blood cell correction factor for traumatic lumbar puncture.

Kannarkat GT, Darrow J, Moghekar A.

J Neurol Sci. 2022 Jan 15;432:120097. doi: 10.1016/j.jns.2021.120097. Epub 2021 Dec 15.

PMID: 34929498

Before and after: lumbar puncture complicated by cerebral venous sinus thrombosis.

Kannarkat GT, Moghekar A.

Neurol Sci. 2022 Feb;43(2):1469-1470. doi: 10.1007/s10072-021-05773-3. Epub 2021 Nov 24.

PMID: 34817730 No abstract available.

Reinspection of a Clinical Proteomics Tumor Analysis Consortium (CPTAC) Dataset with Cloud Computing Reveals Abundant Post-Translational Modifications and Protein Sequence Variants.

Prakash A, Taylor L, Varkey M, Hoxie N, Mohammed Y, Goo YA, Peterman S, Moghekar A, Yuan Y, Glaros T, Steele JR, Faridi P, Parihari S, Srivastava S, Otto JJ, Nyalwidhe JO, Semmes OJ, Moran MF, Madugundu A, Mun DG, Pandey A, Mahoney KE, Shabanowitz J, Saxena S, Orsburn BC.

Cancers (Basel). 2021 Oct 9;13(20):5034. doi: 10.3390/cancers13205034.

PMID: 34680183 Free PMC article.

Personality Associations With Amyloid and Tau: Results From the Baltimore Longitudinal Study of Aging and Meta-analysis.

Terracciano A, Bilgel M, Aschwanden D, Luchetti M, Stephan Y, Moghekar AR, Wong DF, Ferrucci L, Sutin AR, Resnick SM.

Biol Psychiatry. 2022 Feb 15;91(4):359-369. doi: 10.1016/j.biopsych.2021.08.021. Epub 2021 Sep 3.

PMID: 34663503

Cognitive and gait outcomes after primary endoscopic third ventriculostomy in adults with chronic obstructive hydrocephalus.

Zwimpfer TJ, Salterio N, Williams MA, Holubkov R, Katzen H, Luciano MG, Moghekar A, Nagel SJ, Wisoff JH, Golomb J, McKhann GM, Edwards RJ, Hamilton MG; Adult Hydrocephalus Clinical Research Network.

J Neurosurg. 2021 Sep 17;136(3):887-894. doi: 10.3171/2021.3.JNS203424. Print 2022 Mar 1.

PMID: 34534954

Predictors of cognitive impairment in pseudotumor cerebri.

Fermo OP, Rao A, Schwartzbaum A, Sengupta S, Zhang Y, Wang J, Moghekar A.

Neurol Neurochir Pol. 2021;55(4):394-402. doi: 10.5603/PJNNS.a2021.0057. Epub 2021 Aug 11.

PMID: 34379319

Evaluation of the effect comorbid Parkinson syndrome on normal pressure hydrocephalus assessment.

Davis A, Gulyani S, Manthripragada L, Luciano M, Moghekar A, Yasar S.

Clin Neurol Neurosurg. 2021 Aug;207:106810. doi: 10.1016/j.clineuro.2021.106810. Epub 2021 Jul 10.

PMID: 34280677

A proposed framework for cerebral venous congestion.

Arun A, Amans MR, Higgins N, Brinjikji W, Sattur M, Satti SR, Nakaji P, Luciano M, Huisman TA, Moghekar A, Pereira VM, Meng R, Fargen K, Hui FK.

Neuroradiol J. 2022 Feb;35(1):94-111. doi: 10.1177/19714009211029261. Epub 2021 Jul 5.

PMID: 34224274

2022

2024

2021

Intracranial Hypotension Related Skull Remodeling with Enophthalmos.

McCulley TJ, Moghekar A.

Orbit. 2021 Oct;40(5):444-446. doi: 10.1080/01676830.2021.1939729. Epub 2021 Jun 15.

PMID: 34130604 No abstract available.

Cerebrospinal fluid lipidomics for biomarkers of Alzheimer's disease.

Byeon SK, Madugundu AK, Jain AP, Bhat FA, Jung JH, Renuse S, Darrow J, Bakker A, Albert M, Moghekar A, Pandey A.

Mol Omics. 2021 Jun 14;17(3):454-463. doi: 10.1039/d0mo00186d.

PMID: 34125126 Free PMC article.

Cerebrospinal fluid in COVID-19 neurological complications: Neuroaxonal damage, anti-SARS-Cov2 antibodies but no evidence of cytokine storm.

Garcia MA, Barreras PV, Lewis A, Pinilla G, Sokoll LJ, Kickler T, Mostafa H, Caturegli M, Moghekar A, Fitzgerald KC; Hopkins Neuro-COVID-19 Group, Pardo CA.

J Neurol Sci. 2021 Aug 15;427:117517. doi: 10.1016/j.jns.2021.117517. Epub 2021 May 31.

PMID: 34090021 Free PMC article.

Blood-Brain Barrier Breakdown in Relationship to Alzheimer and Vascular Disease.

Lin Z, Sur S, Liu P, Li Y, Jiang D, Hou X, Darrow J, Pillai JJ, Yasar S, Rosenberg P, Albert M, Moghekar A, Lu H.

Ann Neurol. 2021 Aug;90(2):227-238. doi: 10.1002/ana.26134. Epub 2021 Jun 5.

PMID: 34041783 Free PMC article.

Assessing the predictive value of common gait measure for predicting falls in patients presenting with suspected normal pressure hydrocephalus.

Davis A, Luciano M, Moghekar A, Yasar S.

BMC Neurol. 2021 Feb 8;21(1):60. doi: 10.1186/s12883-021-02068-0.

PMID: 33557773 Free PMC article.

MarkVCID cerebral small vessel consortium: I. Enrollment, clinical, fluid protocols.

Wilcock D, Jicha G, Blacker D, Albert MS, D'Orazio LM, Elahi FM, Fornage M, Hinman JD, Knoefel J, Kramer J, Kryscio RJ, Lamar M, Moghekar A, Prestopnik J, Ringman JM, Rosenberg G, Sagare A, Satizabal CL, Schneider J, Seshadri S, Sur S, Tracy RP, Yasar S, Williams V, Singh H, Mazina L, Helmer KG, Corriveau RA, Schwab K, Kivisäkk P, Greenberg SM; MarkVCID Consortium.

Alzheimers Dement. 2021 Apr;17(4):704-715. doi: 10.1002/alz.12215. Epub 2021 Jan 21.

PMID: 33480172

Cerebrospinal fluid in COVID-19 neurological complications: no cytokine storm or neuroinflammation.

Garcia MA, Barreras PV, Lewis A, Pinilla G, Sokoll LJ, Kickler T, Mostafa H, Caturegli M, Moghekar A, Fitzgerald KC, Pardo CA.

medRxiv. 2021 Jan 12:2021.01.10.20249014. doi: 10.1101/2021.01.10.20249014. Preprint.

PMID: 33469596 Free PMC article.

Systematic volumetric analysis predicts response to CSF drainage and outcome to shunt surgery in idiopathic normal pressure hydrocephalus.

Wu D, Moghekar A, Shi W, Blitz AM, Mori S.

Eur Radiol. 2021 Jan 3. doi: 10.1007/s00330-020-07531-z. Online ahead of print.

PMID: 33389035

Effect of Patient-Specific Preanalytic Variables on CSF Aβ1-42 Concentrations Measured on an Automated Chemiluminescent Platform.

Darrow JA, Calabro A, Gannon S, Orusakwe A, Esquivel R, Traynham CJ, Rao A, Gulyani S, Khingelova K, Bandeen-Roche K, Albert M, Moghekar A.

J Appl Lab Med. 2021 Mar 1;6(2):397-408. doi: 10.1093/jalm/jfaa145.

PMID: 33249440

Quantitative proteomic analysis of the frontal cortex in Alzheimer's disease.

Sathe G, Albert M, Darrow J, Saito A, Troncoso J, Pandey A, Moghekar A.

J Neurochem. 2021 Mar;156(6):988-1002. doi: 10.1111/jnc.15116. Epub 2020 Jul 22.

PMID: 32614981

Mid-term assessment of transverse sinus stent patency in 104 patients treated for intracranial hypertension secondary to dural sinus stenosis.

El Mekabaty A, Pearl MS, Moghekar A, Gailloud P.

J Neurointerv Surg. 2021 Feb;13(2):182-186. doi: 10.1136/neurintsurg-2020-015949. Epub 2020 Jun 10.

PMID: 32522787

2020

Association of midlife vascular risk and AD biomarkers with subsequent cognitive decline.

Pettigrew C, Soldan A, Wang J, Wang MC, Arthur K, Moghekar A, Gottesman RF, Albert M.

Neurology. 2020 Dec 8;95(23):e3093-e3103. doi: 10.1212/WNL.0000000000010946. Epub 2020 Sep 28.

PMID: 32989109

Association of cerebrovascular reactivity and Alzheimer pathologic markers with cognitive performance.

Sur S, Lin Z, Li Y, Yasar S, Rosenberg P, Moghekar A, Hou X, Kalyani R, Hazel K, Pottanat G, Xu C, van Zijl P, Pillai J, Liu P, Albert M, Lu H.

Neurology. 2020 Aug 25;95(8):e962-e972. doi: 10.1212/WNL.0000000000010133. Epub 2020 Jul 13.

PMID: 32661101

Brain Oxygen Extraction Is Differentially Altered by Alzheimer's and Vascular Diseases.

Jiang D, Lin Z, Liu P, Sur S, Xu C, Hazel K, Pottanat G, Darrow J, Pillai JJ, Yasar S, Rosenberg P, Moghekar A, Albert M, Lu H.

J Magn Reson Imaging. 2020 Dec;52(6):1829-1837. doi: 10.1002/jmri.27264. Epub 2020 Jun 21.

PMID: 32567195

Development of a novel method for the quantification of tyrosine 39 phosphorylated α- and β-synuclein in human cerebrospinal fluid.

Na CH, Sathe G, Rosenthal LS, Moghekar AR, Dawson VL, Dawson TM, Pandey A.

Clin Proteomics. 2020 May 4;17:13. doi: 10.1186/s12014-020-09277-8. eCollection 2020.

PMID: 32390785 Free PMC article.

Standardized regression-based clinical change score cutoffs for normal pressure hydrocephalus.

Davis A, Yasar S, Emerman I, Gulyani S, Khingelova K, Rao A, Manthripragada L, Luciano M, Moghekar A.

BMC Neurol. 2020 Apr 16;20(1):140. doi: 10.1186/s12883-020-01719-y.

PMID: 32299370 Free PMC article.

General Anesthesia Alters Intracranial Venous Pressures During Transverse Sinus Stenting.

El Mekabaty A, Gottschalk A, Moghekar A, Obusez E, Khan M, Chung C, Spiotta A, Luciano MG, Hui FK.

World Neurosurg. 2020 Jun;138:e712-e717. doi: 10.1016/j.wneu.2020.03.050. Epub 2020 Mar 16.

PMID: 32194272

Multiplexed Phosphoproteomic Study of Brain in Patients with Alzheimer's Disease and Age-Matched Cognitively Healthy Controls.

Sathe G, Mangalaparthi KK, Jain A, Darrow J, Troncoso J, Albert M, Moghekar A, Pandey A.

OMICS. 2020 Apr;24(4):216-227. doi: 10.1089/omi.2019.0191. Epub 2020 Mar 17.

PMID: 32182160 Free PMC article.

Association of peripheral inflammatory markers with connectivity in large-scale functional brain networks of non-demented older adults.

Walker KA, Gross AL, Moghekar AR, Soldan A, Pettigrew C, Hou X, Lu H, Alfini AJ, Bilgel M, Miller MI, Albert MS, Walston J.

Brain Behav Immun. 2020 Jul;87:388-396. doi: 10.1016/j.bbi.2020.01.006. Epub 2020 Jan 11.

PMID: 31935468

Cognitive reserve and rate of change in Alzheimer's and cerebrovascular disease biomarkers among cognitively normal individuals.

Pettigrew C, Soldan A, Zhu Y, Cai Q, Wang MC, Moghekar A, Miller MI, Singh B, Martinez O, Fletcher E, DeCarli C, Albert M.

Neurobiol Aging. 2020 Apr;88:33-41. doi: 10.1016/j.neurobiolaging.2019.12.003. Epub 2019 Dec 17.

PMID: 31932050 Free PMC article.

High-Resolution MRI for Evaluation of Ventriculostomy Tubes: Assessment of Positioning and Proximal Patency.

Blitz AM, Huynh PP, Bonham LW, Gujar SK, Sorte DE, Moghekar A, Luciano MG, Rigamonti D.

AJNR Am J Neuroradiol. 2020 Jan;41(1):57-63. doi: 10.3174/ajnr.A6320.

PMID: 31924603 Free PMC article.

White matter hyperintensities and CSF Alzheimer disease biomarkers in preclinical Alzheimer disease.

Soldan A, Pettigrew C, Zhu Y, Wang MC, Moghekar A, Gottesman RF, Singh B, Martinez O, Fletcher E, DeCarli C, Albert M; BIOCARD Research Team.

Neurology. 2020 Mar 3;94(9):e950-e960. doi: 10.1212/WNL.0000000000008864. Epub 2019 Dec 30.

PMID: 31888969 Free PMC article.

Medial temporal lobe white matter pathway variability is associated with individual differences in episodic memory in cognitively normal older adults.

Alm KH, Faria AV, Moghekar A, Pettigrew C, Soldan A, Mori S, Albert M, Bakker A.

Neurobiol Aging. 2020 Mar;87:78-88. doi: 10.1016/j.neurobiolaging.2019.11.011. Epub 2019 Nov 21.

PMID: 31874745 Free PMC article.

2019

Plasma Markers of Inflammation Linked to Clinical Progression and Decline During Preclinical AD.

Gross AL, Walker KA, Moghekar AR, Pettigrew C, Soldan A, Albert MS, Walston JD.

Front Aging Neurosci. 2019 Sep 6;11:229. doi: 10.3389/fnagi.2019.00229. eCollection 2019.

PMID: 31555121 Free PMC article.

Tau pathology in cognitively normal older adults.

Ziontz J, Bilgel M, Shafer AT, Moghekar A, Elkins W, Helphrey J, Gomez G, June D, McDonald MA, Dannals RF, Azad BB, Ferrucci L, Wong DF, Resnick SM.

Alzheimers Dement (Amst). 2019 Sep 6;11:637-645. doi: 10.1016/j.dadm.2019.07.007. eCollection 2019 Dec.

PMID: 31517026 Free PMC article.

Resting-State Functional Connectivity Is Associated With Cerebrospinal Fluid Levels of the Synaptic Protein NPTX2 in Non-demented Older Adults.

Soldan A, Moghekar A, Walker KA, Pettigrew C, Hou X, Lu H, Miller MI, Alfini A, Albert M, Xu D, Xiao MF, Worley P; BIOCARD Research Team.

Front Aging Neurosci. 2019 Jun 7;11:132. doi: 10.3389/fnagi.2019.00132. eCollection 2019.

PMID: 31231205 Free PMC article.

The Occipital Emissary Vein: A Possible Marker for Pseudotumor Cerebri.

Hedjoudje A, Piveteau A, Gonzalez-Campo C, Moghekar A, Gailloud P, San Millán D.

AJNR Am J Neuroradiol. 2019 Jun;40(6):973-978. doi: 10.3174/ajnr.A6061. Epub 2019 May 9.

PMID: 31072972 Free PMC article.

Brain Oxygen Extraction by Using MRI in Older Individuals: Relationship to Apolipoprotein E Genotype and Amyloid Burden.

Lin Z, Sur S, Soldan A, Pettigrew C, Miller M, Oishi K, Bilgel M, Moghekar A, Pillai JJ, Albert M, Lu H.

Radiology. 2019 Jul;292(1):140-148. doi: 10.1148/radiol.2019182726. Epub 2019 Apr 23.

PMID: 31012816 Free PMC article.

Identifying Changepoints in Biomarkers During the Preclinical Phase of Alzheimer's Disease.

Younes L, Albert M, Moghekar A, Soldan A, Pettigrew C, Miller MI.

Front Aging Neurosci. 2019 Apr 2;11:74. doi: 10.3389/fnagi.2019.00074. eCollection 2019.

PMID: 31001108 Free PMC article.

Direct Lung Ultrasound Evaluation (CLUE): A novel technique for monitoring extravascular lung water in donor lungs.

Ayyat KS, Okamoto T, Niikawa H, Itoda Y, Dugar S, Latifi SQ, Lebovitz DJ, Moghekar A, McCurry KR.

J Heart Lung Transplant. 2019 Jul;38(7):757-766. doi: 10.1016/j.healun.2019.03.005. Epub 2019 Mar 13.

PMID: 31000373

ATN profiles among cognitively normal individuals and longitudinal cognitive outcomes.

Soldan A, Pettigrew C, Fagan AM, Schindler SE, Moghekar A, Fowler C, Li QX, Collins SJ, Carlsson C, Asthana S, Masters CL, Johnson S, Morris JC, Albert M, Gross AL.

Neurology. 2019 Apr 2;92(14):e1567-e1579. doi: 10.1212/WNL.0000000000007248. Epub 2019 Mar 6.

PMID: 30842300 Free PMC article.

Quantitative Proteomic Profiling of Cerebrospinal Fluid to Identify Candidate Biomarkers for Alzheimer's Disease.

Sathe G, Na CH, Renuse S, Madugundu AK, Albert M, Moghekar A, Pandey A.

Proteomics Clin Appl. 2019 Jul;13(4):e1800105. doi: 10.1002/prca.201800105. Epub 2019 Jan 25.

PMID: 30578620 Free PMC article.

Neuropathologic, genetic, and longitudinal cognitive profiles in primary age-related tauopathy (PART) and Alzheimer's disease.

Bell WR, An Y, Kageyama Y, English C, Rudow GL, Pletnikova O, Thambisetty M, O'Brien R, Moghekar AR, Albert MS, Rabins PV, Resnick SM, Troncoso JC.

Alzheimers Dement. 2019 Jan;15(1):8-16. doi: 10.1016/j.jalz.2018.07.215. Epub 2018 Dec 11.

PMID: 30465754 Free PMC article.

2018

Does Phase-Contrast Imaging through the Cerebral Aqueduct Predict the Outcome of Lumbar CSF Drainage or Shunt Surgery in Patients with Suspected Adult Hydrocephalus?

Blitz AM, Shin J, Balédent O, Pagé G, Bonham LW, Herzka DA, Moghekar AR, Rigamonti D.

AJNR Am J Neuroradiol. 2018 Dec;39(12):2224-2230. doi: 10.3174/ajnr.A5857. Epub 2018 Nov 22.

PMID: 30467214 Free PMC article.

Does the Presence or Absence of DESH Predict Outcomes in Adult Hydrocephalus?

Ahmed AK, Luciano M, Moghekar A, Shin J, Aygun N, Sair HI, Rigamonti D, Blitz AM.

AJNR Am J Neuroradiol. 2018 Nov;39(11):2022-2026. doi: 10.3174/ajnr.A5820. Epub 2018 Oct 25.

PMID: 30361433 Free PMC article.

Phosphotyrosine profiling of human cerebrospinal fluid.

Sathe G, Na CH, Renuse S, Madugundu A, Albert M, Moghekar A, Pandey A.

Clin Proteomics. 2018 Sep 12;15:29. doi: 10.1186/s12014-018-9205-1. eCollection 2018.

PMID: 30220890 Free PMC article.

Sex-specific genetic predictors of Alzheimer's disease biomarkers.

Deming Y, Dumitrescu L, Barnes LL, Thambisetty M, Kunkle B, Gifford KA, Bush WS, Chibnik LB, Mukherjee S, De Jager PL, Kukull W, Huentelman M, Crane PK, Resnick SM, Keene CD, Montine TJ, Schellenberg GD, Haines JL, Zetterberg H, Blennow K, Larson EB, Johnson SC, Albert M, Moghekar A, Del Aguila JL, Fernandez MV, Budde J, Hassenstab J, Fagan AM, Riemenschneider M, Petersen RC, Minthon L, Chao MJ, Van Deerlin VM, Lee VM, Shaw LM, Trojanowski JQ, Peskind ER, Li G, Davis LK, Sealock JM, Cox NJ; Alzheimer’s Disease Neuroimaging Initiative (ADNI); Alzheimer Disease Genetics Consortium (ADGC), Goate AM, Bennett DA, Schneider JA, Jefferson AL, Cruchaga C, Hohman TJ.

Acta Neuropathol. 2018 Dec;136(6):857-872. doi: 10.1007/s00401-018-1881-4. Epub 2018 Jul 2.

PMID: 29967939 Free PMC article.

Toward dynamic lumbar puncture guidance using needle-based single-element ultrasound imaging.

Zhang HK, Kim Y, Lin M, Paredes M, Kannan K, Moghekar A, Durr NJ, Boctor EM.

J Med Imaging (Bellingham). 2018 Apr;5(2):021224. doi: 10.1117/1.JMI.5.2.021224. Epub 2018 Apr 2.

PMID: 29651451 Free PMC article.

Non-contrast MR imaging of blood-brain barrier permeability to water.

Lin Z, Li Y, Su P, Mao D, Wei Z, Pillai JJ, Moghekar A, van Osch M, Ge Y, Lu H.

Magn Reson Med. 2018 Oct;80(4):1507-1520. doi: 10.1002/mrm.27141. Epub 2018 Mar 1.

PMID: 29498097 Free PMC article.

Predicting progression from normal cognition to mild cognitive impairment for individuals at 5 years.

Albert M, Zhu Y, Moghekar A, Mori S, Miller MI, Soldan A, Pettigrew C, Selnes O, Li S, Wang MC.

Brain. 2018 Mar 1;141(3):877-887. doi: 10.1093/brain/awx365.

PMID: 29365053 Free PMC article.

2017

Cognitive reserve and long-term change in cognition in aging and preclinical Alzheimer's disease.

Soldan A, Pettigrew C, Cai Q, Wang J, Wang MC, Moghekar A, Miller MI, Albert M; BIOCARD Research Team.

Neurobiol Aging. 2017 Dec;60:164-172. doi: 10.1016/j.neurobiolaging.2017.09.002. Epub 2017 Sep 11.

PMID: 28968586 Free PMC article.

Progressive medial temporal lobe atrophy during preclinical Alzheimer's disease.

Pettigrew C, Soldan A, Sloane K, Cai Q, Wang J, Wang MC, Moghekar A, Miller MI, Albert M; BIOCARD Research Team.

Neuroimage Clin. 2017 Aug 25;16:439-446. doi: 10.1016/j.nicl.2017.08.022. eCollection 2017.

PMID: 28879085 Free PMC article.

Alzheimer's disease pathology and shunt surgery outcome in normal pressure hydrocephalus.

Yasar S, Jusue-Torres I, Lu J, Robison J, Patel MA, Crain B, Carson KA, Hoffberger J, Batra S, Sankey E, Moghekar A, Rigamonti D.

PLoS One. 2017 Aug 7;12(8):e0182288. doi: 10.1371/journal.pone.0182288. eCollection 2017.

PMID: 28786990 Free PMC article. Clinical Trial.

Spontaneous Intracranial Hypotension after Vestibular Schwannoma Resection Due to an Unexpected Pathology: Tarlov Cysts.

Pross SE, Sharon JD, Lim M, Moghekar A, Rao A, Carey JP.

Cureus. 2017 May 19;9(5):e1261. doi: 10.7759/cureus.1261.

PMID: 28652945 Free PMC article.

Conversion Discriminative Analysis on Mild Cognitive Impairment Using Multiple Cortical Features from MR Images.

Guo S, Lai C, Wu C, Cen G; Alzheimer's Disease Neuroimaging Initiative.

Front Aging Neurosci. 2017 May 18;9:146. doi: 10.3389/fnagi.2017.00146. eCollection 2017.

PMID: 28572766 Free PMC article.

Venous Sinus Stenting in the Management of Patients with Intracranial Hypertension Manifesting with Skull Base Cerebrospinal Fluid Leaks.

Iyer RR, Solomon D, Moghekar A, Goodwin CR, Stewart CM, Ishii M, Gailloud P, Gallia GL.

World Neurosurg. 2017 Oct;106:103-112. doi: 10.1016/j.wneu.2017.06.087. Epub 2017 Jun 20.

PMID: 28645586

Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers.

Deming Y, Li Z, Kapoor M, Harari O, Del-Aguila JL, Black K, Carrell D, Cai Y, Fernandez MV, Budde J, Ma S, Saef B, Howells B, Huang KL, Bertelsen S, Fagan AM, Holtzman DM, Morris JC, Kim S, Saykin AJ, De Jager PL, Albert M, Moghekar A, O'Brien R, Riemenschneider M, Petersen RC, Blennow K, Zetterberg H, Minthon L, Van Deerlin VM, Lee VM, Shaw LM, Trojanowski JQ, Schellenberg G, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Peskind ER, Li G, Di Narzo AF; Alzheimer’s Disease Neuroimaging Initiative (ADNI); Alzheimer Disease Genetic Consortium (ADGC), Kauwe JS, Goate AM, Cruchaga C.

Acta Neuropathol. 2017 May;133(5):839-856. doi: 10.1007/s00401-017-1685-y. Epub 2017 Feb 28.

PMID: 28247064 Free PMC article.

Predictors for venous sinus stent retreatment in patients with idiopathic intracranial hypertension.

El Mekabaty A, Obuchowski NA, Luciano MG, John S, Chung CY, Moghekar A, Jones S, Hui FK.

J Neurointerv Surg. 2017 Dec;9(12):1228-1232. doi: 10.1136/neurintsurg-2016-012803. Epub 2016 Dec 13.

PMID: 27965382

Genome-wide, high-content siRNA screening identifies the Alzheimer's genetic risk factor FERMT2 as a major modulator of APP metabolism.

Chapuis J, Flaig A, Grenier-Boley B, Eysert F, Pottiez V, Deloison G, Vandeputte A, Ayral AM, Mendes T, Desai S, Goate AM, Kauwe JSK, Leroux F, Herledan A, Demiautte F, Bauer C, Checler F, Petersen RC, Blennow K, Zetterberg H, Minthon L, Van Deerlin VM, Lee VM, Shaw LM, Trojanowski JQ, Albert M, Moghekar A, O'Brien R, Peskind ER, Malmanche N, Schellenberg GD, Dourlen P, Song OR, Cruchaga C, Amouyel P, Deprez B, Brodin P, Lambert JC; ADGC, Alzheimer’s Disease Neuroimaging Initiative.

Acta Neuropathol. 2017 Jun;133(6):955-966. doi: 10.1007/s00401-016-1652-z. Epub 2016 Dec 8.

PMID: 27933404 Free PMC article.

Computerized Cognitive Tests Are Associated with Biomarkers of Alzheimer's Disease in Cognitively Normal Individuals 10 Years Prior.

Soldan A, Pettigrew C, Moghekar A, Albert M; BIOCARD Research Team.

J Int Neuropsychol Soc. 2016 Nov;22(10):968-977. doi: 10.1017/S1355617716000722.

PMID: 27903332 Free PMC article.

Alpha-2 macroglobulin in Alzheimer's disease: a marker of neuronal injury through the RCAN1 pathway.

Varma VR, Varma S, An Y, Hohman TJ, Seddighi S, Casanova R, Beri A, Dammer EB, Seyfried NT, Pletnikova O, Moghekar A, Wilson MR, Lah JJ, O'Brien RJ, Levey AI, Troncoso JC, Albert MS, Thambisetty M.

Mol Psychiatry. 2017 Jan;22(1):13-23. doi: 10.1038/mp.2016.206. Epub 2016 Nov 22.

PMID: 27872486 Free PMC article.

The impact of surgical resection on headache disability and quality of life in patients with colloid cyst.

Kone L, Chaichana KL, Rincon-Torroella J, Snyman C, Moghekar A, Quiñones-Hinojosa A.

Cephalalgia. 2017 Apr;37(5):442-451. doi: 10.1177/0333102416648654. Epub 2016 May 10.

PMID: 27165491